• Low Dose Naltrexone (LDN) works with your endorphin and immune systems to reduce overall oxidative stress—targeting a number of age-related mechanisms. As evidenced in various studies and successful use cases over the last 40 years, LDN has been shown to improve the body’s ability to defend against age-related diseases.

Background & History

  • Low Dose Naltrexone (LDN) refers to prescribed doses below 10mg per day (4.5mg/daily is most common)

  • Naltrexone has been prescribed and successfully used for over 40 years with an outstanding safety record at doses 10-20x above LDN

  • When administered in low doses, Naltrexone exhibits novel and paradoxical effects for a variety of conditions

  • As discovered by Dr. Ian S. Zagon and his team at Hershey Medical Center in 1980, Naltrexone also has effects against cancer

  • Naltrexone was approved by the FDA in 1985 to treat opiate dependencies at dosages between 50mg-100mg per day

  • Since 1985, LDN has also been used to treat autoimmune diseases and viral infections

  • Later, the FDA also approved the drug to treat obesity and weight loss

  • Hundreds of clinical studies have shown LDN to reduce inflammation

  • Dr. Z, Chief Medical Officer at AgelessRx, has prescribed LDN for years with successful results in a variety of patients . Learn More

  • Increases endorphin levels

  • Overall better mood and feeling of well being

  • Modulates the immune system

  • Reduces chance of autoimmunity

  • Lowers markers of inflammation in the body

  • Reduces fatigue and brain fog

  • Strong clinical evidence in reducing chronic pain 

  • Encourages weight loss in some patients

Longevity Benefits

LDN has not been approved by FDA for these uses, but there are multiple scientific studies that have shown these benefits.

Purchase LDN

  1. Complete medical intake form

  2. Receive medical approval or follow-up

  3. Get medication shipped to your door

Starting at - $40/Month

* Prescription products, such as LDN,  require an online consultation with a physician to determine if a prescription is appropriate. See below for important safety information. Benefits outlined on Agelessrx.com are based on third party studies. LDN is offered as a subscription service you can cancel at any time.

* For refills, click here.

Important Safety Information & Common Side Effects

  • Vivid dreams

  • Mild anxiety

  • Insomnia

  • Headache

During the first three to five days of taking LDN, you may experience mild to moderate levels of the above side effects. Side effects typically diminish on their own by day five. To reduce the risk of side effects, AgelessRx advisors[VS1]  recommend patients start with a ½ tab (2.25mg) for the first two weeks with a gradual increase to the 4.5mg dose.

Note:  Please stop taking any dosage of Naltrexone a minimum of 48-hours before any surgical procedure or medical diagnostic requiring sedation, such as surgery or a colonoscopy. If you are not sure if you need to stop Naltrexone, please ask your doctor ordering the test or procedure. Additionally, Naltrexone cannot be taken in conjunction with opioids/painkillers. If you need to stop taking Naltrexone for a surgery, and accompanying pain killers are prescribed, you may resume LDN only 48-hours after you take your last painkiller. 

For a full list of possible side effects Click Here​

If you are interested in a prescription product, AgelessRx will assist in setting up a visit for you with a licensed physician, who will evaluate whether or not you are an appropriate candidate for the prescription product. If appropriate, may write you a prescription for the product which you can fill at the pharmacy of your choice.